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Search for Metastasis in Oncology and Hematology
Physician-authored summaries on the latest research on metastasis, editorials on metastasis, and perspectives on metastasis - drawn from the top medical journals.
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You searched for: metastasis in Oncology and Hematology
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Clodronate for Prostate Cancer: An Update
- September 22, 2009
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Long-term results revealed an overall survival benefit for men with metastatic, but not locally advanced, disease.- Reviewing:
- Dearnaley DP et al., Lancet Oncol 2009 Sep; 10:872.
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Lymph Node Biopsy in Older Patients with Breast Cancer
- April 14, 2009
- Henry Mark Kuerer, MD, PhD, FACS
- Oncology and Hematology
A clinical model identifies low-risk patients who could be spared such evaluations.- Reviewing:
- Chagpar AB et al., Ann Surg 2009 Mar; 249:455.
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Bisphosphonates for Nonmetastatic Prostate Cancer? Free
- June 11, 2007
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Clodronate did not improve bone-metastasis–free survival or overall survival in patients with nonmetastatic prostate cancer.- Reviewing:
- Mason MD et al., J Natl Cancer Inst 2007 May 16; 99:765-76.
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Brain Metastases in Triple-Negative Breast Cancer
- May 26, 2009
- William J. Gradishar, MD
- Oncology and Hematology
Cumulative incidence at 5 years was nearly 10%.- Reviewing:
- Dawood S et al., Ann Oncol 2009 Apr; 20:621.
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New Therapies for Thyroid Cancer
- December 2, 2008
- Barbara A. Murphy, MD
- Oncology and Hematology
Sorafenib and axitinib demonstrated activity against recurrent and metastatic disease.- Reviewing:
- Gupta-Abramson V et al., J Clin Oncol 2008 Oct 10; 26:4714. Cohen EEW et al., J Clin Oncol 2008 Oct 10; 26:4708.
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Radical Prostatectomy vs. Watchful Waiting
- September 16, 2008
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Surgery was associated with lower risk for mortality and metastases in men younger than 65.- Reviewing:
- Bill-Axelson A et al., J Natl Cancer Inst 2008 Aug 20; 100:1144. Wilt TJ., J Natl Cancer Inst 2008 Aug 20; 100:1123.
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Radiofrequency Ablation of Malignant Lung Nodules
- August 12, 2008
- Lin-Chi Chen, MD, PhD
- Oncology and Hematology
RFA generated complete response in a high percentage of patients with unresectable malignancies.- Reviewing:
- Lencioni R et al., Lancet Oncol 2008 Jul; 9:621.
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Lapatinib for Treatment of Metastatic Brain Metastases
- May 13, 2008
- William J. Gradishar, MD
- Oncology and Hematology
This antitumor agent failed to provide a predefined CNS response, but its use was associated with volumetric reductions in target lesions.- Reviewing:
- Lin NU et al., J Clin Oncol 2008 Apr 20; 26:1993.
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Venous Thrombosis and Occult Malignancy
- February 12, 2008
- David Green, MD, PhD
- Oncology and Hematology
Predictors of occult malignancy among patients with VTE were older age, unprovoked VTE, bilateral DVT, and anemia.- Reviewing:
- Trujillo-Santos J et al., J Thromb Haemost 2008 Feb; 6:251.
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Using MRI to Detect Bone Metastases in High-Risk Prostate Cancer Patients Free
- August 21, 2007
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
MRI is more accurate than bone scans or plain radiographs for detecting bone metastases, but is better detection always the best course?- Reviewing:
- Lecouvet FE et al., J Clin Oncol 2007 Aug 1; 25:3281-7.
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Palliative Radiotherapy for Patients with Bone Metastases
- June 25, 2007
- Barbara A. Murphy, MD
- Oncology and Hematology
SF radiation provided equivalent pain control but had higher retreatment rates than did MF radiation.- Reviewing:
- Chow E et al., J Clin Oncol 2007 Apr 10; 25:1423-36.
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Axillary Lymph Node Nanometastases Free
- December 18, 2006
- William J. Gradishar, MD
- Oncology and Hematology
These results suggest that even minimal involvement of lymph nodes confers a poor prognosis in breast cancer patients.- Reviewing:
- Querzoli P et al., Clin Cancer Res 2006 Nov 15; 12:6696-701.
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Octreotide Treatment for Neuroendocrine Tumors
- November 10, 2009
- David H. Ilson, MD, PhD
- Oncology and Hematology
In treatment-naive patients, octreotide substantially lengthened time to tumor progression.- Reviewing:
- Rinke A et al., J Clin Oncol 2009 Oct 1; 27:4656.
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A Model for Chuvash Polycythemia
- July 28, 2009
- David Green, MD, PhD
- Oncology and Hematology
Main features of the disease are replicated in a novel mutant zebrafish model.- Reviewing:
- van Rooijen E et al., Blood 2009 Jun 18; 113:6449.
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Are Disseminated Tumor Cells Prognostic in Prostate Cancer?
- April 7, 2009
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Cytokeratin-positive cells detected postoperatively in bone marrow conferred excess risk for subsequent metastases.- Reviewing:
- Weckermann D et al., J Clin Oncol 2009 Apr 1; 27:1549. Scher HI and Pantel K., J Clin Oncol 2009 Apr 1; 27:1531.
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Adjuvant Radiotherapy for Locally Advanced Prostate Cancer
- March 24, 2009
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Compared with patients who underwent observation after prostatectomy, those who received adjuvant RT had lower risk for metastasis and longer overall survival.- Reviewing:
- Thompson IM et al., J Urol 2009 Mar; 181:956.
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Surrogate Endpoints for Prostate Cancer Survival
- March 17, 2009
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Distant metastasis and treatment failure at 3 years might be surrogates for survival at 10 years.- Reviewing:
- Ray ME et al., J Natl Cancer Inst 2009 Feb 18; 101:228.
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Predicting Venous Thromboembolism in Cancer Patients
- November 18, 2008
- David Green, MD, PhD
- Oncology and Hematology
Patients with VTE had higher levels of soluble platelet selectin than did those without VTE.- Reviewing:
- Ay C et al., Blood 2008 Oct 1; 112:2703.
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Laparoscopic Colectomy for Colon Cancer Free
- August 5, 2008
- Henry Mark Kuerer, MD, PhD, FACS
- Oncology and Hematology
Survival advantages were associated with laparoscopic versus open colectomy in patients with advanced disease.- Reviewing:
- Lacy AM et al., Ann Surg 2008 Jul; 248:1.
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Sorafenib Lengthens Survival in Patients with Advanced Hepatocellular Cancer
- July 23, 2008
- David H. Ilson, MD, PhD
- Oncology and Hematology
Survival was 3 months longer for patients given sorafenib than for those given placebo.- Reviewing:
- Llovet JM et al., N Engl J Med 2008 Jul 24; 359:378.
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